Two-photon absorption of polyfluorene aggregates stabilized by insulin amyloid fibrils
Journal article, 2015

We report on the photophysical and optical properties of a polyfluorene derivative (PFO) and its binding to the amyloid-forming protein insulin. The complexation is based on weak supramolecular interactions between amyloid fibrils and PFO in dissolved and aggregated forms. In particular, complexes of polyfluorene aggregates display sizeable two-photon absorption when stabilized by insulin fibril nanotemplates. We propose that a two-photon absorption enhancement mechanism is related to the combination of through-bond and through-space interactions of PFO. The findings reported here suggest that polyfluorene aggregates offer good nonlinear absorption properties and can be used as molecular markers for amyloid fibril recognition.

Author

Piotr Hanczyc

Chalmers, Chemistry and Chemical Engineering, Chemistry and Biochemistry, Physical Chemistry

A. Justyniarski

Wrocław University of Science and Technology

Desta Antenehe Gedefaw

Chalmers, Chemistry and Chemical Engineering, Applied Chemistry, Polymer Technology

Mats Andersson

Chalmers, Chemistry and Chemical Engineering, Applied Chemistry, Polymer Technology

University of South Australia

Marek Samoc

Wrocław University of Science and Technology

Christian Müller

Chalmers, Chemistry and Chemical Engineering, Applied Chemistry, Polymer Technology

RSC Advances

2046-2069 (ISSN)

Vol. 5 61 49363-49368

Subject Categories

Physical Chemistry

DOI

10.1039/c5ra08302h

More information

Latest update

6/24/2019