Two-photon absorption of polyfluorene aggregates stabilized by insulin amyloid fibrils
Journal article, 2015
We report on the photophysical and optical properties of a polyfluorene derivative (PFO) and its binding to the amyloid-forming protein insulin. The complexation is based on weak supramolecular interactions between amyloid fibrils and PFO in dissolved and aggregated forms. In particular, complexes of polyfluorene aggregates display sizeable two-photon absorption when stabilized by insulin fibril nanotemplates. We propose that a two-photon absorption enhancement mechanism is related to the combination of through-bond and through-space interactions of PFO. The findings reported here suggest that polyfluorene aggregates offer good nonlinear absorption properties and can be used as molecular markers for amyloid fibril recognition.
Author
Piotr Hanczyc
Chalmers, Chemistry and Chemical Engineering, Chemistry and Biochemistry
A. Justyniarski
Wrocław University of Science and Technology
Desta Antenehe Gedefaw
Chalmers, Chemistry and Chemical Engineering, Applied Chemistry
Mats Andersson
Chalmers, Chemistry and Chemical Engineering, Applied Chemistry
University of South Australia
Marek Samoc
Wrocław University of Science and Technology
Christian Müller
Chalmers, Chemistry and Chemical Engineering, Applied Chemistry
RSC Advances
20462069 (eISSN)
Vol. 5 61 49363-49368Subject Categories
Physical Chemistry
DOI
10.1039/c5ra08302h