Electronic polymers in lipid membranes
Journal article, 2015

Electrical interfaces between biological cells and man-made electrical devices exist in many forms, but it remains a challenge to bridge the different mechanical and chemical environments of electronic conductors (metals, semiconductors) and biosystems. Here we demonstrate soft electrical interfaces, by integrating the metallic polymer PEDOT-S into lipid membranes. By preparing complexes between alkyl-ammonium salts and PEDOT-S we were able to integrate PEDOT-S into both liposomes and in lipid bilayers on solid surfaces. This is a step towards efficient electronic conduction within lipid membranes. We also demonstrate that the PEDOT-S@alkyl-ammonium:lipid hybrid structures created in this work affect ion channels in the membrane of Xenopus oocytes, which shows the possibility to access and control cell membrane structures with conductive polyelectrolytes.

Author

P.K. Johansson

Linköping University

University of Washington

David Jullesson

Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology

A. Elfwing

Linköping University

S.I. Liin

Linköping University

C. Musumeci

Linköping University

E. Zeglio

Linköping University

F. Elinder

University of Washington

N. Solin

Linköping University

Olle Inganaes

Linköping University

Scientific Reports

2045-2322 (ISSN)

Vol. 5

Subject Categories

Biophysics

DOI

10.1038/srep11242

More information

Latest update

10/15/2018