Low Circulating Acute Brain-Derived Neurotrophic Factor Levels Are Associated With Poor Long-Term Functional Outcome After Ischemic Stroke.
Journal article, 2016
Brain-derived neurotrophic factor (BDNF) plays important roles in brain plasticity and repair, and it influences stroke outcomes in animal models. Circulating BDNF concentrations are lowered in patients with traumatic brain injury, and low BDNF predicts poor recovery after this injury. We sought to investigate whether circulating concentrations of BDNF are altered in the acute phase of ischemic stroke and whether they are associated with short- or long-term functional outcome.
serum
risk factors
pathogenesis
brain-derived neurotrophic factor
stroke
Author
Tara M Stanne
University of Gothenburg
N David Åberg
University of Gothenburg
Staffan Nilsson
University of Gothenburg
Chalmers, Mathematical Sciences, Mathematical Statistics
Katarina Jood
University of Gothenburg
Christian Blomstrand
University of Gothenburg
Ulf Andreasson
University of Gothenburg
Kaj Blennow
University of Gothenburg
Henrik Zetterberg
University of Gothenburg
Jörgen Isgaard
University of Gothenburg
Johan Svensson
University of Gothenburg
Christina Jern
University of Gothenburg
Stroke
0039-2499 (ISSN) 1524-4628 (eISSN)
Vol. 47 7 1943-1945Subject Categories
Neurosciences
DOI
10.1161/STROKEAHA.115.012383
PubMed
27301948