Low Circulating Acute Brain-Derived Neurotrophic Factor Levels Are Associated With Poor Long-Term Functional Outcome After Ischemic Stroke.
Artikel i vetenskaplig tidskrift, 2016

Brain-derived neurotrophic factor (BDNF) plays important roles in brain plasticity and repair, and it influences stroke outcomes in animal models. Circulating BDNF concentrations are lowered in patients with traumatic brain injury, and low BDNF predicts poor recovery after this injury. We sought to investigate whether circulating concentrations of BDNF are altered in the acute phase of ischemic stroke and whether they are associated with short- or long-term functional outcome.

serum

risk factors

pathogenesis

brain-derived neurotrophic factor

stroke

Författare

Tara M Stanne

Göteborgs universitet

N David Åberg

Göteborgs universitet

Staffan Nilsson

Göteborgs universitet

Chalmers, Matematiska vetenskaper, matematisk statistik

Katarina Jood

Göteborgs universitet

Christian Blomstrand

Göteborgs universitet

Ulf Andreasson

Göteborgs universitet

Kaj Blennow

Göteborgs universitet

Henrik Zetterberg

Göteborgs universitet

Jörgen Isgaard

Göteborgs universitet

Johan Svensson

Göteborgs universitet

Christina Jern

Göteborgs universitet

Stroke

0039-2499 (ISSN) 1524-4628 (eISSN)

Vol. 47 1943-1945

Ämneskategorier

Neurovetenskaper

DOI

10.1161/STROKEAHA.115.012383

PubMed

27301948