Low Circulating Acute Brain-Derived Neurotrophic Factor Levels Are Associated With Poor Long-Term Functional Outcome After Ischemic Stroke.
Artikel i vetenskaplig tidskrift, 2016
Brain-derived neurotrophic factor (BDNF) plays important roles in brain plasticity and repair, and it influences stroke outcomes in animal models. Circulating BDNF concentrations are lowered in patients with traumatic brain injury, and low BDNF predicts poor recovery after this injury. We sought to investigate whether circulating concentrations of BDNF are altered in the acute phase of ischemic stroke and whether they are associated with short- or long-term functional outcome.
serum
risk factors
pathogenesis
brain-derived neurotrophic factor
stroke
Författare
Tara M Stanne
Göteborgs universitet
N David Åberg
Göteborgs universitet
Staffan Nilsson
Göteborgs universitet
Chalmers, Matematiska vetenskaper, Matematisk statistik
Katarina Jood
Göteborgs universitet
Christian Blomstrand
Göteborgs universitet
Ulf Andreasson
Göteborgs universitet
Kaj Blennow
Göteborgs universitet
Henrik Zetterberg
Göteborgs universitet
Jörgen Isgaard
Göteborgs universitet
Johan Svensson
Göteborgs universitet
Christina Jern
Göteborgs universitet
Stroke
0039-2499 (ISSN) 1524-4628 (eISSN)
Vol. 47 7 1943-1945Ämneskategorier
Neurovetenskaper
DOI
10.1161/STROKEAHA.115.012383
PubMed
27301948