NaB integrated graphene oxide membranes for enhanced cell viability and stem cell properties of human adipose stem cells
Journal article, 2016

Here we present the integration of boron (NaB) with graphene oxide (GO) to develop a new class of membranes which are biocompatible and cost-effective for cell and tissue culture studies. Ethanol (EtOH) assisted the uniform dispersion of GO flakes on top of a glass substrate. We investigated the effect of a GO + NaB membrane on the growth and proliferation of hASCs. hASCs showed better cell viability on NaB integrated GO membranes compared to their respective controls. The concentrations of NaB and GO are 0.02% and 1/20 of stock (0.024%) respectively. To our knowledge this is the first time that enhanced cell proliferation and attachment ability of hASCs with NaB integrated GO membranes has been observed. Our study provides a platform for the development of 3D-GO scaffold systems combined with NaB in tissue engineering.

Author

Venkata Raghu Mokkapati

Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology

Neslihan P. Tasli

T.C. Yeditepe Universitesi

Zaeema Khan

Sabanci Universitesi

Ali Tufani

Sabanci Universitesi

Santosh Pandit

Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology

Hikmet Budak

Sabanci Universitesi

Fikrettin Sahin

T.C. Yeditepe Universitesi

RSC Advances

2046-2069 (ISSN)

Vol. 6 61 56159-56165

Subject Categories

Bioinformatics and Systems Biology

DOI

10.1039/c6ra07414f

More information

Created

10/7/2017