Adsorption of Amino Acids and Glutamic Acid-Based Surfactants on Imogolite Clays
Journal article, 2017

Aluminum oxide surfaces are of utmost interest in different biotech applications, in particular for their use as adjuvants (i.e., booster of the immune response against infectious agents in vaccines production). In this framework, imogolite clays combine the chemical flexibility of an exposed alumina surface with 1D nanostructure. This work reports on the interaction between amino acids and imogolite, using turbidimetry, zeta-potential measurements, and Fourier transform infrared spectroscopy as main characterization tools. Amino acids with different side chain functional groups were investigated, showing that glutamic acid (Glu) has the strongest affinity for the imogolite surface. This was exploited to prepare a composite material made of a synthetic surfactant bearing a Glu polar head and a hydrophobic C-12 alkyl tail, adsorbed onto the surface of imogolite. The adsorption of a model drug (rhodamine B isothiocyanate) by the hybrid was evaluated both in water and in physiological saline conditions. The findings of this paper suggest that the combination between the glutamate headgroup and imogolite represents a promising platform for the fabrication of hybrid nanostructures with tailored functionalities.

synthetic imogolite







aluminosilicate nanotubes



carbon nanotubes

Materials Science


M. Bonini

University of Florence

A. Gabbani

University of Florence

S. Del Buffa

University of Florence

F. Ridi

University of Florence

P. Baglioni

University of Florence

Romain Bordes

SuMo Biomaterials

Chalmers, Chemistry and Chemical Engineering, Applied Chemistry, Applied Surface Chemistry

Krister Holmberg

Chalmers, Chemistry and Chemical Engineering, Applied Chemistry, Applied Surface Chemistry

Competence Centre for Catalysis (KCK)

SuMo Biomaterials


07437463 (ISSN) 15205827 (eISSN)

Vol. 33 9 2411-2419

Subject Categories

Physical Chemistry

Chemical Sciences


Basic sciences



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3/2/2018 7