Adsorption of Amino Acids and Glutamic Acid-Based Surfactants on Imogolite Clays
Artikel i vetenskaplig tidskrift, 2017

Aluminum oxide surfaces are of utmost interest in different biotech applications, in particular for their use as adjuvants (i.e., booster of the immune response against infectious agents in vaccines production). In this framework, imogolite clays combine the chemical flexibility of an exposed alumina surface with 1D nanostructure. This work reports on the interaction between amino acids and imogolite, using turbidimetry, zeta-potential measurements, and Fourier transform infrared spectroscopy as main characterization tools. Amino acids with different side chain functional groups were investigated, showing that glutamic acid (Glu) has the strongest affinity for the imogolite surface. This was exploited to prepare a composite material made of a synthetic surfactant bearing a Glu polar head and a hydrophobic C-12 alkyl tail, adsorbed onto the surface of imogolite. The adsorption of a model drug (rhodamine B isothiocyanate) by the hybrid was evaluated both in water and in physiological saline conditions. The findings of this paper suggest that the combination between the glutamate headgroup and imogolite represents a promising platform for the fabrication of hybrid nanostructures with tailored functionalities.

synthetic imogolite

nanofibers

nanoparticles

hydrogels

adjuvant

tio2

alumina

aluminosilicate nanotubes

aspartic-acid

Chemistry

carbon nanotubes

Materials Science

Författare

M. Bonini

Universita degli Studi di Firenze

A. Gabbani

Universita degli Studi di Firenze

S. Del Buffa

Universita degli Studi di Firenze

F. Ridi

Universita degli Studi di Firenze

P. Baglioni

Universita degli Studi di Firenze

Romain Bordes

SuMo Biomaterials

Chalmers, Kemi och kemiteknik, Tillämpad kemi, Teknisk ytkemi

Krister Holmberg

Chalmers, Kemi och kemiteknik, Tillämpad kemi, Teknisk ytkemi

Kompetenscentrum katalys (KCK)

SuMo Biomaterials

Langmuir

0743-7463 (ISSN) 1520-5827 (eISSN)

Vol. 33 9 2411-2419

Ämneskategorier

Fysikalisk kemi

Kemi

Fundament

Grundläggande vetenskaper

DOI

10.1021/acs.langmuir.6b04414

Mer information

Senast uppdaterat

2018-03-02