The chimeric nature of the genomes of marine magnetotactic coccoid-ovoid bacteria defines a novel group of Proteobacteria
Journal article, 2017

Magnetotactic bacteria (MTB) are a group of phylogenetically and physiologically diverse Gram-negative bacteria that synthesize intracellular magnetic crystals named magnetosomes. MTB are affiliated with three classes of Proteobacteria phylum, Nitrospirae phylum, Omnitrophica phylum and probably with the candidate phylum Latescibacteria. The evolutionary origin and physiological diversity of MTB compared with other bacterial taxonomic groups remain to be illustrated. Here, we analysed the genome of the marine magneto-ovoid strain MO-1 and found that it is closely related to Magnetococcus marinus MC-1. Detailed analyses of the ribosomal proteins and whole proteomes of 390 genomes reveal that, among the Proteobacteria analysed, only MO-1 and MC-1 have coding sequences (CDSs) with a similarly high proportion of origins from Alphaproteobacteria, Betaproteobacteria, Deltaproteobacteria and Gammaproteobacteria. Interestingly, a comparative metabolic network analysis with anoxic network enzymes from sequenced MTB and non-MTB successfully allows the eventual prediction of an organism with a metabolic profile compatible for magnetosome production. Altogether, our genomic analysis reveals multiple origins of MO-1 and M. marinus MC-1 genomes and suggests a metabolism-restriction model for explaining whether a bacterium could become an MTB upon acquisition of magnetosome encoding genes.

LCB

apparatus

France.

reveals

magnetosome gene clusters

RS

Marseille

flagellar

sequence

phylum nitrospirae

metabolic networks

candidatus magnetobacterium

Author

Boyang Ji

Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology

S. D. Zhang

Chinese Academy of Sciences

Centre national de la recherche scientifique (CNRS)

Laboratoire de Chimie Bacterienne

W. J. Zhang

Centre national de la recherche scientifique (CNRS)

Chinese Academy of Sciences

China Agricultural University

Laboratoire de Chimie Bacterienne

Z. Rouy

Universite d' Evry Val d'Essonne

Genomique Metabolique

Centre national de la recherche scientifique (CNRS)

F. Alberto

Laboratoire de Chimie Bacterienne

Centre national de la recherche scientifique (CNRS)

C. L. Santini

Laboratoire de Chimie Bacterienne

Centre national de la recherche scientifique (CNRS)

S. Mangenot

The French Alternative Energies and Atomic Energy Commission (CEA)

S. Gagnot

Laboratoire de Chimie Bacterienne

N. Philippe

Laboratoire de Chimie Bacterienne

Aix Marseille University

N. Pradel

Centre national de la recherche scientifique (CNRS)

Aix Marseille University

L. C. Zhang

Laboratoire de Chimie Bacterienne

Xinxiang Medical College

S. Tempel

Laboratoire de Chimie Bacterienne

Y. Li

China Agricultural University

Centre national de la recherche scientifique (CNRS)

C. Medigue

Universite d' Evry Val d'Essonne

Centre national de la recherche scientifique (CNRS)

Genomique Metabolique

B. Henrissat

Aix Marseille University

P. M. Coutinho

Aix Marseille University

V. Barbe

The French Alternative Energies and Atomic Energy Commission (CEA)

E. Talla

Laboratoire de Chimie Bacterienne

L. F. Wu

Laboratoire de Chimie Bacterienne

Centre national de la recherche scientifique (CNRS)

Environmental Microbiology

1462-2912 (ISSN) 1462-2920 (eISSN)

Vol. 19 3 1103-1119

Areas of Advance

Building Futures (2010-2018)

Subject Categories

Biological Sciences

Roots

Basic sciences

DOI

10.1111/1462-2920.13637

More information

Latest update

9/7/2018 1