The chimeric nature of the genomes of marine magnetotactic coccoid-ovoid bacteria defines a novel group of Proteobacteria
Journal article, 2017
Magnetotactic bacteria (MTB) are a group of phylogenetically and physiologically diverse Gram-negative bacteria that synthesize intracellular magnetic crystals named magnetosomes. MTB are affiliated with three classes of Proteobacteria phylum, Nitrospirae phylum, Omnitrophica phylum and probably with the candidate phylum Latescibacteria. The evolutionary origin and physiological diversity of MTB compared with other bacterial taxonomic groups remain to be illustrated. Here, we analysed the genome of the marine magneto-ovoid strain MO-1 and found that it is closely related to Magnetococcus marinus MC-1. Detailed analyses of the ribosomal proteins and whole proteomes of 390 genomes reveal that, among the Proteobacteria analysed, only MO-1 and MC-1 have coding sequences (CDSs) with a similarly high proportion of origins from Alphaproteobacteria, Betaproteobacteria, Deltaproteobacteria and Gammaproteobacteria. Interestingly, a comparative metabolic network analysis with anoxic network enzymes from sequenced MTB and non-MTB successfully allows the eventual prediction of an organism with a metabolic profile compatible for magnetosome production. Altogether, our genomic analysis reveals multiple origins of MO-1 and M. marinus MC-1 genomes and suggests a metabolism-restriction model for explaining whether a bacterium could become an MTB upon acquisition of magnetosome encoding genes.
LCB
apparatus
France.
reveals
magnetosome gene clusters
RS
Marseille
flagellar
sequence
phylum nitrospirae
metabolic networks
candidatus magnetobacterium
Author
Boyang Ji
Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology
S. D. Zhang
Chinese Academy of Sciences
Centre national de la recherche scientifique (CNRS)
Laboratoire de Chimie Bacterienne
W. J. Zhang
Centre national de la recherche scientifique (CNRS)
Chinese Academy of Sciences
China Agricultural University
Laboratoire de Chimie Bacterienne
Z. Rouy
University of Évry Val d'Essonne
Genomique Metabolique
Centre national de la recherche scientifique (CNRS)
F. Alberto
Laboratoire de Chimie Bacterienne
Centre national de la recherche scientifique (CNRS)
C. L. Santini
Laboratoire de Chimie Bacterienne
Centre national de la recherche scientifique (CNRS)
S. Mangenot
The French Alternative Energies and Atomic Energy Commission (CEA)
S. Gagnot
Laboratoire de Chimie Bacterienne
N. Philippe
Laboratoire de Chimie Bacterienne
Aix Marseille University
N. Pradel
Centre national de la recherche scientifique (CNRS)
Aix Marseille University
L. C. Zhang
Laboratoire de Chimie Bacterienne
Xinxiang Medical College
S. Tempel
Laboratoire de Chimie Bacterienne
Y. Li
China Agricultural University
Centre national de la recherche scientifique (CNRS)
C. Medigue
University of Évry Val d'Essonne
Centre national de la recherche scientifique (CNRS)
Genomique Metabolique
B. Henrissat
Aix Marseille University
P. M. Coutinho
Aix Marseille University
V. Barbe
The French Alternative Energies and Atomic Energy Commission (CEA)
E. Talla
Laboratoire de Chimie Bacterienne
L. F. Wu
Laboratoire de Chimie Bacterienne
Centre national de la recherche scientifique (CNRS)
Environmental Microbiology
1462-2912 (ISSN) 1462-2920 (eISSN)
Vol. 19 3 1103-1119Areas of Advance
Building Futures (2010-2018)
Subject Categories
Biological Sciences
Roots
Basic sciences
DOI
10.1111/1462-2920.13637