The chimeric nature of the genomes of marine magnetotactic coccoid-ovoid bacteria defines a novel group of Proteobacteria
Artikel i vetenskaplig tidskrift, 2017

Magnetotactic bacteria (MTB) are a group of phylogenetically and physiologically diverse Gram-negative bacteria that synthesize intracellular magnetic crystals named magnetosomes. MTB are affiliated with three classes of Proteobacteria phylum, Nitrospirae phylum, Omnitrophica phylum and probably with the candidate phylum Latescibacteria. The evolutionary origin and physiological diversity of MTB compared with other bacterial taxonomic groups remain to be illustrated. Here, we analysed the genome of the marine magneto-ovoid strain MO-1 and found that it is closely related to Magnetococcus marinus MC-1. Detailed analyses of the ribosomal proteins and whole proteomes of 390 genomes reveal that, among the Proteobacteria analysed, only MO-1 and MC-1 have coding sequences (CDSs) with a similarly high proportion of origins from Alphaproteobacteria, Betaproteobacteria, Deltaproteobacteria and Gammaproteobacteria. Interestingly, a comparative metabolic network analysis with anoxic network enzymes from sequenced MTB and non-MTB successfully allows the eventual prediction of an organism with a metabolic profile compatible for magnetosome production. Altogether, our genomic analysis reveals multiple origins of MO-1 and M. marinus MC-1 genomes and suggests a metabolism-restriction model for explaining whether a bacterium could become an MTB upon acquisition of magnetosome encoding genes.

LCB

apparatus

France.

reveals

magnetosome gene clusters

RS

Marseille

flagellar

sequence

phylum nitrospirae

metabolic networks

candidatus magnetobacterium

Författare

Boyang Ji

Chalmers, Biologi och bioteknik, Systembiologi

S. D. Zhang

Chinese Academy of Sciences

Centre national de la recherche scientifique (CNRS)

Laboratoire de Chimie Bacterienne

W. J. Zhang

Centre national de la recherche scientifique (CNRS)

Chinese Academy of Sciences

China Agricultural University

Laboratoire de Chimie Bacterienne

Z. Rouy

Universite d' Evry Val d'Essonne

Genomique Metabolique

Centre national de la recherche scientifique (CNRS)

F. Alberto

Laboratoire de Chimie Bacterienne

Centre national de la recherche scientifique (CNRS)

C. L. Santini

Laboratoire de Chimie Bacterienne

Centre national de la recherche scientifique (CNRS)

S. Mangenot

Le Commissariat à l’Énergie Atomique et aux Énergies Alternatives (CEA)

S. Gagnot

Laboratoire de Chimie Bacterienne

N. Philippe

Laboratoire de Chimie Bacterienne

Aix Marseille Université

N. Pradel

Centre national de la recherche scientifique (CNRS)

Aix Marseille Université

L. C. Zhang

Laboratoire de Chimie Bacterienne

Xinxiang Medical College

S. Tempel

Laboratoire de Chimie Bacterienne

Y. Li

China Agricultural University

Centre national de la recherche scientifique (CNRS)

C. Medigue

Universite d' Evry Val d'Essonne

Centre national de la recherche scientifique (CNRS)

Genomique Metabolique

B. Henrissat

Aix Marseille Université

P. M. Coutinho

Aix Marseille Université

V. Barbe

Le Commissariat à l’Énergie Atomique et aux Énergies Alternatives (CEA)

E. Talla

Laboratoire de Chimie Bacterienne

L. F. Wu

Laboratoire de Chimie Bacterienne

Centre national de la recherche scientifique (CNRS)

Environmental Microbiology

1462-2912 (ISSN) 1462-2920 (eISSN)

Vol. 19 3 1103-1119

Styrkeområden

Building Futures

Ämneskategorier

Biologiska vetenskaper

Fundament

Grundläggande vetenskaper

DOI

10.1111/1462-2920.13637

Mer information

Senast uppdaterat

2018-09-07