Metagenomics of microbial and viral life in terrestrial geothermal environments
Journal article, 2017

Geothermally heated regions of Earth, such as terrestrial volcanic areas (fumaroles, hot springs, and geysers) and deep-sea hydrothermal vents, represent a variety of different environments populated by extremophilic archaeal and bacterial microorganisms. Since most of these microbes thriving in such harsh biotopes, they are often recalcitrant to cultivation; therefore, ecological, physiological and phylogenetic studies of these microbial populations have been hampered for a long time. More recently, culture-independent methodologies coupled with the fast development of next generation sequencing technologies as well as with the continuous advances in computational biology, have allowed the production of large amounts of metagenomic data. Specifically, these approaches have assessed the phylogenetic composition and functional potential of microbial consortia thriving within these habitats, shedding light on how extreme physico-chemical conditions and biological interactions have shaped such microbial communities. Metagenomics allowed to better understand that the exposure to an extreme range of selective pressures in such severe environments, accounts for genomic flexibility and metabolic versatility of microbial and viral communities, and makes extreme-and hyper-thermophiles suitable for bioprospecting purposes, representing an interesting source for novel thermostable proteins that can be potentially used in several industrial processes.

Enzyme

CRISPR

Geothermal environments

Hyperthermophiles

Microbial and viral metagenomics

Author

A. Strazzulli

Universita degli Studi di Napoli Federico II

Consiglo Nazionale Delle Richerche

Salvatore Fusco

Chalmers, Biology and Biological Engineering, Industrial Biotechnology

B. Cobucci-Ponzano

Consiglo Nazionale Delle Richerche

M. Moracci

Consiglo Nazionale Delle Richerche

Universita degli Studi di Napoli Federico II

Patrizia Contursi

Universita degli Studi di Napoli Federico II

Reviews in Environmental Science and Biotechnology

1569-1705 (ISSN)

Vol. 16 3 425-454

Subject Categories

Environmental Sciences

Environmental Biotechnology

DOI

10.1007/s11157-017-9435-0

More information

Latest update

9/6/2018 1