In silico analysis of human metabolism: Reconstruction, contextualization and application of genome-scale models
Review article, 2017
Drug development
Human metabolism
Constraint-based analysis
Genome-scale metabolic model
Topological analysis
Author
Jun Geng
Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology
Jens B Nielsen
Technical University of Denmark (DTU)
Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology
Royal Institute of Technology (KTH)
Current Opinion in Systems Biology
24523100 (eISSN)
Vol. 2 29-38Subject Categories
Pharmaceutical Sciences
Bioinformatics (Computational Biology)
Bioinformatics and Systems Biology
DOI
10.1016/j.coisb.2017.01.001