Dual polarity MALDI imaging mass spectrometry on the same pixel points reveals spatial lipid localizations at high-spatial resolutions in rat small intestine
Journal article, 2018
Sensitive laser desorption/ionization obtained via a sublimation-coated 1,5-diaminonaphthalene (1,5-DAN) matrix allowed dual polarity MALDI-IMS analysis on the same pixel points across the jejunal mucosal region in rat small intestine which yielded high-spatial-resolution (10 μm) ion images of several lipid species correlated with the same histological features.
Author
I. Kaya
University of Gothenburg
Eva Jennische
University of Gothenburg
Stefan Lange
University of Gothenburg
Per Malmberg
Chalmers, Chemistry and Chemical Engineering, Chemistry and Biochemistry
University of Gothenburg
Analytical Methods
1759-9660 (ISSN) 1759-9679 (eISSN)
Vol. 10 21 2428-2435Subject Categories
Atom and Molecular Physics and Optics
Computer Vision and Robotics (Autonomous Systems)
Medical Image Processing
DOI
10.1039/c8ay00645h