Biochemical control systems for small molecule damage in plants
Review article, 2018

As a system, plant metabolism is far from perfect: small molecules (metabolites, cofactors, coenzymes, and inorganic molecules) are frequently damaged by unwanted enzymatic or spontaneous reactions. Here, we discuss the emerging principles in small molecule damage biology. We propose that plants evolved at least three distinct systems to control small molecule damage: (i) repair, which returns a damaged molecule to its original state; (ii) scavenging, which converts reactive molecules to harmless products; and (iii) steering, in which the possible formation of a damaged molecule is suppressed. We illustrate the concept of small molecule damage control in plants by describing specific examples for each of these three categories. We highlight interesting insights that we expect future research will provide on those systems, and we discuss promising strategies to discover new small molecule damage-control systems in plants.

scavenging systems

Abiotic stress

enzyme promiscuity

metabolic intermediates

reactive oxygen species

small molecules

repair system

molecule damage

reactive carbonyl species

glyoxalase system

steering systems

Author

M. Hüdig

Heinrich Heine University Düsseldorf

J. Schmitz

Heinrich Heine University Düsseldorf

Martin Engqvist

Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology

V. G. Maurino

Heinrich Heine University Düsseldorf

Plant Signaling and Behavior

1559-2316 (ISSN)

Vol. 13 5 e1477906

Subject Categories

Other Engineering and Technologies not elsewhere specified

Control Engineering

DOI

10.1080/15592324.2018.1477906

More information

Latest update

8/28/2018