Martin Engqvist

2023

Chiral Alcohols from Alkenes and Water: Directed Evolution of a Styrene Hydratase

2023

A general model to predict small molecule substrates of enzymes based on machine and deep learning

2022

Basin-scale biogeography of marine phytoplankton reflects cellular-scale optimization of metabolism and physiology

2022

Dataset for suppressors of amyloid-beta toxicity and their functions in recombinant protein production in yeast

2022

Deep learning-based k(cat) prediction enables improved enzyme-constrained model reconstruction

2022

Directed Evolution of (R)-2-Hydroxyglutarate Dehydrogenase Improves 2-Oxoadipate Reduction by 2 Orders of Magnitude

2022

Learning deep representations of enzyme thermal adaptation

2022

Suppressors of amyloid-β toxicity improve recombinant protein production in yeast by reducing oxidative stress and tuning cellular metabolism

2022

Engineering Saccharomyces cerevisiae for the production and secretion of Affibody molecules

2022

Modeling-Assisted Design of Thermostable Benzaldehyde Lyases from Rhodococcus erythropolis for Continuous Production of α-Hydroxy Ketones

2022

Discovery of Two Novel Oxidases Using a High-Throughput Activity Screen

2021

Performance of Regression Models as a Function of Experiment Noise

2021

Deep learning allows genome-scale prediction of Michaelis constants from structural features

2021

Experimental and computational investigation of enzyme functional annotations uncovers misannotation in the EC 1.1.3.15 enzyme class

2021

Adaptation of a Microfluidic qPCR System for Enzyme Kinetic Studies

Expanding functional protein sequence spaces using generative adversarial networks

Investigation of functional annotations to enzyme classes reveals an extensive annotation error

2021

The Yeast eIF2 Kinase Gcn2 Facilitates H2O2-Mediated Feedback Inhibition of Both Protein Synthesis and Endoplasmic Reticulum Oxidative Folding during Recombinant Protein Production

2021

CAZyme prediction in ascomycetous yeast genomes guides discovery of novel xylanolytic species with diverse capacities for hemicellulose hydrolysis

2020

A synthesis of bacterial and archaeal phenotypic trait data

2020

Elimination of rNMPs from mitochondrial DNA has no effect on its stability

2020

Quantitative analysis of amino acid metabolism in liver cancer links glutamate excretion to nucleotide synthesis

2020

Different routes of protein folding contribute to improved protein production in saccharomyces cerevisiae

Machine Learning Applied to Predicting Microorganism Growth Temperatures and Enzyme Catalytic Optima

Applications of protein engineering and directed evolution in plant research

2019

3D-Printed Phenacrylate Decarboxylase Flow Reactors for the Chemoenzymatic Synthesis of 4-Hydroxystilbene

2019

DNA polymerase η contributes to genome-wide lagging strand synthesis

2018

Correlating enzyme annotations with a large set of microbial growth temperatures reveals metabolic adaptations to growth at diverse temperatures

Biochemical control systems for small molecule damage in plants

Ribonucleotides incorporated by the yeast mitochondrial DNA polymerase are not repaired

Nucleotide pools dictate the identity and frequency of ribonucleotide incorporation in mitochondrial DNA

Metabolic engineering of photorespiration

Simultaneous mapping and quantitation of ribonucleotides in human mitochondrial DNA

Highlighting the need for systems-level experimental characterization of plant metabolic enzymes

2016

The influence of alternative pathways of respiration that utilize branched-chain amino acids following water shortage in Arabidopsis

2015

Adaptive mutations in sugar metabolism restore growth on glucose in a pyruvate decarboxylase negative yeast strain

GLYCOLATE OXIDASE3, a Glycolate Oxidase Homolog of Yeast l-Lactate Cytochrome c Oxidoreductase, Supports l-Lactate Oxidation in Roots of Arabidopsis

ANT: Software for Generating and Evaluating Degenerate Codons for Natural and Expanded Genetic Codes

Arabidopsis book

Directed evolution of gloeobacter violaceus rhodopsin spectral properties

Directed evolution of a far-red fluorescent rhodopsin

Mitochondrial 2-hydroxyglutarate metabolism

Plants Possess a Cyclic Mitochondrial Metabolic Pathway similar to the Mammalian Metabolic Repair Mechanism Involving Malate Dehydrogenase and l-2-Hydroxyglutarate Dehydrogenase

Archaerhodopsin variants with enhanced voltage-sensitive fluorescence in mammalian and Caenorhabditis elegans neurons

D-2-hydroxyglutarate metabolism is linked to photorespiration in the shm1-1 mutant

D-Lactate dehydrogenase as a marker gene allows positive selection of transgenic plants

Transgenic introduction of a glycolate oxidative cycle into A. thaliana chloroplasts leads to growth improvement

Plant D-2-hydroxyglutarate dehydrogenase participates in the catabolism of lysine especially during senescence

Two D-2-hydroxy-acid dehydrogenases in arabidopsis thaliana with catalytic capacities to participate in the last reactions of the methylglyoxal and β-oxidation pathways

HAG2/MYB76 and HAG3/MYB29 exert a specific and coordinated control on the regulation of aliphatic glucosinolate biosynthesis in Arabidopsis thaliana

Effect of poly(ethylene glycol) on enzymatic hydrolysis and adsorption of cellulase enzymes to pretreated lignocellulose