Multifunctional ZnO/SiO2 Core/Shell Nanoparticles for Bioimaging and Drug Delivery Application
Journal article, 2020

Semiconducting nanoparticles with luminescent properties are used as detection probes and drug carriers in in-vitro and in-vivo analysis. ZnO nanoparticles, due to its biocompatibility and low cost, have shown potential application in bioimaging and drug delivery. Thus, ZnO/SiO2 core/shell nanoparticle was synthesised by wet chemical method for fluorescent probing and drug delivery application. The synthesised core/shell nanomaterial was characterized using XRD, FTIR, UV-VIS spectroscopy, Raman spectroscopy, TEM and PL analysis. The silicon shell enhances the photoluminescence and aqueous stability of the pure ZnO nanoparticles. The porous surface of the shell acts as a carrier for sustained release of curcumin. The synthesized core/shell particle shows high cell viability, hemocompatibility and promising florescent property. [Figure not available: see fulltext.].

Bioimaging

Biocompatible

Core/shell

Sustainable drug release

Author

A. P.S. Prasanna

SRM Institute of Science and Technology

K. S. Venkataprasanna

SRM Institute of Science and Technology

Balashanmugam Pannerselvam

Anna University Chennai

Vijayshankar Asokan

Chalmers, Chemistry and Chemical Engineering, Energy and Material, Environmental Inorganic Chemistry

R. Sofia Jeniffer

Vellore Institute of Technology

G. Devanand Venkatasubbu

SRM Institute of Science and Technology

Journal of Fluorescence

1053-0509 (ISSN) 1573-4994 (eISSN)

Vol. 30 5 1075-1083

Subject Categories

Other Chemistry Topics

Pharmacology and Toxicology

Biomaterials Science

DOI

10.1007/s10895-020-02578-z

More information

Latest update

10/7/2020