Statistical Inference on Interacting Particle Systems
Licentiate thesis, 2021

Interacting particle systems, and more specifically stochastic dynamical systems, is a mathematical framework which allows for condensed and elegant modelling of complex phenomena undergoing both deterministic and random dynamics. This thesis is concerned with the topic of statistical inference on large systems of interacting particles, with the specific application of in vitro migration of cancer cells. In the first of two papers appended with this thesis, we introduce a novel method of inference based on a higher order numerical approximation of the underlying stochastic differential equations. In the second paper, we formulate a model for glioblastoma cell migration, and conduct inference on this model using microscopy data. This regression shows promising results in its predictive power.

glioblastoma

stochastic process

Bayesian inference

agent based modelling

mathematical biology

MVL15
Opponent: Linus Schumacher

Author

Gustav Lindwall

Chalmers, Mathematical Sciences, Applied Mathematics and Statistics

Fast and precise inference on diffusivity in interacting particle systems

Journal of Mathematical Biology,;Vol. 86(2023)

Journal article

Inference on an interacting diffusion system with application to in vitro glioblastoma migration

Mathematical Medicine and Biology,;Vol. 41(2024)p. 250-276

Journal article

Infrastructure

C3SE (-2020, Chalmers Centre for Computational Science and Engineering)

Areas of Advance

Health Engineering

Subject Categories (SSIF 2011)

Bioinformatics (Computational Biology)

Probability Theory and Statistics

Publisher

Chalmers

MVL15

Online

Opponent: Linus Schumacher

More information

Latest update

9/17/2026