Statistical Inference on Interacting Particle Systems
Licentiatavhandling, 2021

Interacting particle systems, and more specifically stochastic dynamical systems, is a mathematical framework which allows for condensed and elegant modelling of complex phenomena undergoing both deterministic and random dynamics. This thesis is concerned with the topic of statistical inference on large systems of interacting particles, with the specific application of in vitro migration of cancer cells. In the first of two papers appended with this thesis, we introduce a novel method of inference based on a higher order numerical approximation of the underlying stochastic differential equations. In the second paper, we formulate a model for glioblastoma cell migration, and conduct inference on this model using microscopy data. This regression shows promising results in its predictive power.

glioblastoma

stochastic process

Bayesian inference

agent based modelling

mathematical biology

MVL15
Opponent: Linus Schumacher

Författare

Gustav Lindwall

Chalmers, Matematiska vetenskaper, Tillämpad matematik och statistik

Fast and precise inference on diffusivity in interacting particle systems

Journal of Mathematical Biology,;Vol. 86(2023)

Artikel i vetenskaplig tidskrift

Inference on an interacting diffusion system with application to in vitro glioblastoma migration

Mathematical Medicine and Biology,;Vol. 41(2024)p. 250-276

Artikel i vetenskaplig tidskrift

Infrastruktur

C3SE (-2020, Chalmers Centre for Computational Science and Engineering)

Styrkeområden

Hälsa och teknik

Ämneskategorier (SSIF 2011)

Bioinformatik (beräkningsbiologi)

Sannolikhetsteori och statistik

Utgivare

Chalmers

MVL15

Online

Opponent: Linus Schumacher

Mer information

Senast uppdaterat

2026-09-17