Protocells: Milestones and Recent Advances
Review article, 2022
The origin of life is still one of humankind's great mysteries. At the transition between nonliving and living matter, protocells, initially featureless aggregates of abiotic matter, gain the structure and functions necessary to fulfill the criteria of life. Research addressing protocells as a central element in this transition is diverse and increasingly interdisciplinary. The authors review current protocell concepts and research directions, address milestones, challenges and existing hypotheses in the context of conditions on the early Earth, and provide a concise overview of current protocell research methods.
coacervate
protocells
early Earth
origin of life
vesicles
prebiotics
Author
Irep Gözen
University of Oslo
Elif Senem Köksal
University of Oslo
I. Poldsalu
University of Oslo
Lin Xue
University of Oslo
Karolina Spustova
University of Oslo
Esteban Pedrueza Villalmanzo
Chalmers, Chemistry and Chemical Engineering, Chemistry and Biochemistry
University of Gothenburg
Ruslan Ryskulov
Chalmers, Chemistry and Chemical Engineering, Chemistry and Biochemistry
Fanda Meng
Chalmers, Chemistry and Chemical Engineering, Chemistry and Biochemistry
Shandong First Medical University
Aldo Jesorka
Chalmers, Chemistry and Chemical Engineering, Chemistry and Biochemistry
Small
1613-6810 (ISSN) 1613-6829 (eISSN)
Vol. 18 18 2106624Chemical Reaction Networks: signal amplification, spatiotemporal control, and materials (CReaNet)
European Commission (EC) (EC/H2020/812868), 2019-04-01 -- 2023-03-01.
Proto-Opto-Electro-Mechanical Hybrid Systems for Generation-Next Bionic Devices (PROGENY)
European Commission (EC) (EC/H2020/899205), 2021-01-01 -- 2024-06-30.
Subject Categories
Evolutionary Biology
Biochemistry and Molecular Biology
DOI
10.1002/smll.202106624
PubMed
35322554