Construction of S-N-C bond for boosting bacteria-killing by synergistic effect of photocatalysis and nanozyme
Journal article, 2023
Bacterial infection-related diseases are major public safety issues leads to millions of deaths annually. Herein, a porous sulfur doped graphitic carbon nitride (g-SCN) for ecofriendly, metal-free and low systemic toxicity were synthesized. Sulfur doping enables to broaden the absorption spectrum and promote the photocarriers separation for photocatalysis enhancement. Moreover, sulfur element will coordinate with nitrogen, changing the electronic state and endowing g-SCN with the property of nanozyme. More importantly, we established different models and confirmed that S-N-C coordination is the source of peroxidase (POD)-like activity through theory and experiment. The increased specific surface area of g-SCN, ascribing to the porous structure, makes it easier to trap bacteria. With the synergistic effect of photocatalysis and nanozyme, the prepared g-SCN has the ability to kill both gram-negative and gram-positive bacterium, with an antibacterial efficiency up to 100%. This work provides innovative synergistic strategy for constructing nanomaterials for highly efficient antibacterial therapy.
S doped C N 3 4
Synergistic effect
Nanozyme
Photocatalysis
Antibacterial therapy
Author
Longwei Wang
Jinan University
Chinese Academy of Sciences
Zhongwei Yang
Jinan University
Guoxin Song
Jinan University
Zhen You
Chinese Academy of Sciences
Northwest University
Xiaoyu Zhang
Northwest University
Chinese Academy of Sciences
Lin Liu
Jinan University
Jian Zhang
Chalmers, Life Sciences, Systems and Synthetic Biology
Longhua Ding
Jinan University
Na Ren
Jinan University
Aizhu Wang
Jinan University
Jing Liu
Northwest University
Chinese Academy of Sciences
Hong Liu
Shandong University
Jinan University
Xin Yu
Jinan University
Applied Catalysis B: Environmental
0926-3373 (ISSN) 1873-3883 (eISSN)
Vol. 325 122345Subject Categories
Inorganic Chemistry
Other Engineering and Technologies not elsewhere specified
Other Chemistry Topics
DOI
10.1016/j.apcatb.2022.122345