Non-parametric evaluation of memory changes at group and individual level following temporal lobe resection for pharmaco-resistant partial epilepsy
Journal article, 2004
Group versus individual verbal and visuospatial memory outcome following epilepsy surgery was evaluated by a non-parametric method in 25 left and 29 right temporal lobectomy patients. Twenty-five controls were assessed twice. Analyses of change at an individual level evaluated by this statistical approach based on paired-ranks were compared to results with a method based on distances (Reliable Change). The left temporal lobectomy group deteriorated in the two verbal memory variables (p < 0.01 and 0.05). High levels of individual changes unexplained by group patterns were disclosed in the three memory variables analyzed in the patients. Significant individual change, although less pronounced, also occurred in the controls. Group versus individual outcome was adequately distinguished by the non-parametric method. To properly analyze memory change after epilepsy surgery, evaluation at group and individual level ought to combined.
Drug Resistance
Memory/*physiology
Temporal Lobe/*physiopathology/*surgery
Anterior Temporal Lobectomy/*methods
*Statistics
Functional Laterality/physiology
Postoperative Period
Case-Control Studies
Female
Follow-Up Studies
Memory Disorders/physiopathology
Humans
Nonparametric
Adult
Evaluation Studies
Male
Epilepsy
Author
Elisabeth Engman
University of Gothenburg
Lena Andersson-Roswall
University of Gothenburg
Elisabeth Svensson
University of Gothenburg
Chalmers, Department of Mathematical Statistics
Kristina Malmgren
University of Gothenburg
Journal of Clinical and Experimental Neuropsychology
1380-3395 (ISSN) 1744-411X (eISSN)
Vol. 26 7 943-54Subject Categories
Neurology
PubMed
15742544