Non-parametric evaluation of memory changes at group and individual level following temporal lobe resection for pharmaco-resistant partial epilepsy
Artikel i vetenskaplig tidskrift, 2004

Group versus individual verbal and visuospatial memory outcome following epilepsy surgery was evaluated by a non-parametric method in 25 left and 29 right temporal lobectomy patients. Twenty-five controls were assessed twice. Analyses of change at an individual level evaluated by this statistical approach based on paired-ranks were compared to results with a method based on distances (Reliable Change). The left temporal lobectomy group deteriorated in the two verbal memory variables (p < 0.01 and 0.05). High levels of individual changes unexplained by group patterns were disclosed in the three memory variables analyzed in the patients. Significant individual change, although less pronounced, also occurred in the controls. Group versus individual outcome was adequately distinguished by the non-parametric method. To properly analyze memory change after epilepsy surgery, evaluation at group and individual level ought to combined.

Drug Resistance

Memory/*physiology

Temporal Lobe/*physiopathology/*surgery

Anterior Temporal Lobectomy/*methods

*Statistics

Functional Laterality/physiology

Postoperative Period

Case-Control Studies

Female

Follow-Up Studies

Memory Disorders/physiopathology

Humans

Nonparametric

Adult

Evaluation Studies

Male

Epilepsy

Författare

Elisabeth Engman

Göteborgs universitet

Lena Andersson-Roswall

Göteborgs universitet

Elisabeth Svensson

Göteborgs universitet

Chalmers, Institutionen för matematisk statistik

Kristina Malmgren

Göteborgs universitet

Journal of Clinical and Experimental Neuropsychology

1380-3395 (ISSN) 1744-411X (eISSN)

Vol. 26 7 943-54

Ämneskategorier

Neurologi

PubMed

15742544