Modulation and binding properties of extended glycoluril molecular clips
Journal article, 2008
A glycoluril clip (1) provides a deep cavity for binding of guest molecules. Guest species interact
preferentially via hydrogen bonding or ion–lone pair interactions. Complexation-induced
conformational modulation of the cavity wall distance was observed. At higher guest–host ratios,
inclusion compounds with organic guest molecules are obtained. The X-ray crystallographic
structure of 1.(NH4PF6).3CHCl3.2CH3OH shows formation of a network of clips connected via
polar and non-polar interactions.