An unexpected triethylsilane-triggered rearrangement of thioaurones to thioflavonols under SPPS conditions
Journal article, 2008

Thioaurones are converted to a mixture of thiaindenes and thioflavonols when exposed to reaction conditions employed in SPPS, that is, treatment with trifluoroacetic acid in the presence of triethylsilane.

Rearrangement

Chromophores

Thioaurone

Silanes

Peptidomimetics

Reduction

Hemithioindigo

Author

Miranda Varedian

Uppsala University

Vratislav Langer

Chalmers, Chemical and Biological Engineering, Environmental Inorganic Chemistry

Jonas Bergquist

Uppsala University

Adolf Gogoll

Uppsala University

Tetrahedron Letters

0040-4039 (ISSN) 18733581 (eISSN)

Vol. 49 42 6033-6035

Subject Categories

Organic Chemistry

DOI

10.1016/j.tetlet.2008.07.054

More information

Latest update

2/28/2018