An unexpected triethylsilane-triggered rearrangement of thioaurones to thioflavonols under SPPS conditions
Artikel i vetenskaplig tidskrift, 2008
Thioaurones are converted to a mixture of thiaindenes and thioflavonols when exposed to reaction conditions employed in SPPS, that is, treatment with trifluoroacetic acid in the presence of triethylsilane.
Rearrangement
Chromophores
Thioaurone
Silanes
Peptidomimetics
Reduction
Hemithioindigo
Författare
Miranda Varedian
Uppsala universitet
Vratislav Langer
Chalmers, Kemi- och bioteknik, Oorganisk miljökemi
Jonas Bergquist
Uppsala universitet
Adolf Gogoll
Uppsala universitet
Tetrahedron Letters
0040-4039 (ISSN) 18733581 (eISSN)
Vol. 49 42 6033-6035Ämneskategorier
Organisk kemi
DOI
10.1016/j.tetlet.2008.07.054