High-Performance Biosensing Using Arrays of Plasmonic Nanotubes
Journal article, 2010
We show that aligned gold nanotube arrays capable of supporting plasmonic resonances can be used as high performance refractive index sensors in biomolecular binding reactions. A methodology to examine the sensing ability of the inside and outside walls of the nanotube structures is presented. The sensitivity of the plasmonic nanotubes is found to increase as the nanotube walls are exposed, and the sensing characteristic of the inside and outside walls is shown to be different. Finite element simulations showed good qualitative agreement with the observed behavior. Free standing gold nanotubes displayed bulk sensitivities in the region of 250 nm per refractive index unit and a signal-to-noise ratio better than 1000 upon protein binding which is highly competitive with state-of-the-art label-free sensors.
gold nanotubes
label-free biosensing
array
GROWTH
plasmonic
SINGLE
metamaterial
ELECTRODEPOSITION
NANORODS
GOLD
POLYPYRROLE
COLLOIDAL LITHOGRAPHY
LSPR
SENSORS
RESONANCE
finite element simulation
SENSITIVITY
Author
J. McPhillips
Queen's University Belfast
A. Murphy
Queen's University Belfast
Magnus Jonsson
Chalmers, Applied Physics, Biological Physics
W. R. Hendren
Queen's University Belfast
R. Atkinson
Queen's University Belfast
Fredrik Höök
Chalmers, Applied Physics, Biological Physics
A. V. Zayats
Queen's University Belfast
R. J. Pollard
Queen's University Belfast
ACS Nano
1936-0851 (ISSN) 1936-086X (eISSN)
Vol. 4 4 2210-2216Subject Categories
Biophysics
DOI
10.1021/nn9015828