Dual polarity MALDI imaging mass spectrometry on the same pixel points reveals spatial lipid localizations at high-spatial resolutions in rat small intestine
Journal article, 2018

Sensitive laser desorption/ionization obtained via a sublimation-coated 1,5-diaminonaphthalene (1,5-DAN) matrix allowed dual polarity MALDI-IMS analysis on the same pixel points across the jejunal mucosal region in rat small intestine which yielded high-spatial-resolution (10 μm) ion images of several lipid species correlated with the same histological features.


I. Kaya

University of Gothenburg

Eva Jennische

University of Gothenburg

Stefan Lange

University of Gothenburg

Per Malmberg

Chalmers, Chemistry and Chemical Engineering, Chemistry and Biochemistry

University of Gothenburg

Analytical Methods

1759-9660 (ISSN) 1759-9679 (eISSN)

Vol. 10 21 2428-2435

Subject Categories

Atom and Molecular Physics and Optics

Computer Vision and Robotics (Autonomous Systems)

Medical Image Processing



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