Cell factory engineering for improved production of natural products
Review article, 2019

Natural product biosynthesis is inherently linked with the primary metabolism in terms of providing precursors and co-factors. Thus, even though it is important to improve the performance of natural product biosynthetic enzymes in building efficient cell factories, it is equally important to engineer the central carbon metabolism, such that this is adjusted to meet the biosynthetic demand of the desired product.


Jens B Nielsen

BioInnovation Institute

Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology

Technical University of Denmark (DTU)

Natural Product Reports

0265-0568 (ISSN) 1460-4752 (eISSN)

Vol. 36 9 1233-1236

Subject Categories

Other Mechanical Engineering

Other Environmental Engineering

Energy Systems





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