Construction of S-N-C bond for boosting bacteria-killing by synergistic effect of photocatalysis and nanozyme
Journal article, 2023

Bacterial infection-related diseases are major public safety issues leads to millions of deaths annually. Herein, a porous sulfur doped graphitic carbon nitride (g-SCN) for ecofriendly, metal-free and low systemic toxicity were synthesized. Sulfur doping enables to broaden the absorption spectrum and promote the photocarriers separation for photocatalysis enhancement. Moreover, sulfur element will coordinate with nitrogen, changing the electronic state and endowing g-SCN with the property of nanozyme. More importantly, we established different models and confirmed that S-N-C coordination is the source of peroxidase (POD)-like activity through theory and experiment. The increased specific surface area of g-SCN, ascribing to the porous structure, makes it easier to trap bacteria. With the synergistic effect of photocatalysis and nanozyme, the prepared g-SCN has the ability to kill both gram-negative and gram-positive bacterium, with an antibacterial efficiency up to 100%. This work provides innovative synergistic strategy for constructing nanomaterials for highly efficient antibacterial therapy.

S doped C N 3 4

Synergistic effect

Nanozyme

Photocatalysis

Antibacterial therapy

Author

Longwei Wang

Jinan University

Chinese Academy of Sciences

Zhongwei Yang

Jinan University

Guoxin Song

Jinan University

Zhen You

Chinese Academy of Sciences

Northwest University

Xiaoyu Zhang

Northwest University

Chinese Academy of Sciences

Lin Liu

Jinan University

Jian Zhang

Chalmers, Life Sciences, Systems and Synthetic Biology

Longhua Ding

Jinan University

Na Ren

Jinan University

Aizhu Wang

Jinan University

Jing Liu

Northwest University

Chinese Academy of Sciences

Hong Liu

Shandong University

Jinan University

Xin Yu

Jinan University

Applied Catalysis B: Environmental

0926-3373 (ISSN) 1873-3883 (eISSN)

Vol. 325 122345

Subject Categories

Inorganic Chemistry

Other Engineering and Technologies not elsewhere specified

Other Chemistry Topics

DOI

10.1016/j.apcatb.2022.122345

More information

Latest update

7/28/2023