Electron transduction in model enzyme sensors assisted by a photoisomerizable azo-polymer switch
Journal article, 2004

We develop a stochastic model of electronic transduction by means of a rod-like azo-polymer (single peptide molecule doped with a given amount of azo-benzene structural units) in polymer-redox enzyme biosensor. We propose a configuration where the azo-polymer is anchored next to the enzyme reaction center and functions as a light-driven micromechanical actuator shuttling electrons toward the electrode. We show that the output catalytic current is exponentially sensitive to variations in geometrical size of the polymer (a 'switch off' effect) and suggest a scheme where the switching effect is triggered by polymer photoisomerization, resulting in its overall length change. © 2004 Elsevier B.V. All rights reserved.

Author

Marina Voinova

Chalmers, Applied Physics, Condensed Matter Theory

Mats Jonson

Chalmers, Applied Physics, Condensed Matter Theory

Biosensors and Bioelectronics

0956-5663 (ISSN)

Vol. 20 6 1106-1110

Subject Categories

Physical Sciences

DOI

10.1016/j.bios.2004.07.010

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Created

10/6/2017