Topographic SU 8 Substrates for Immobilization of Three-Dimensional Nanotube-Vesicle Networks

Journal article, 2004

A method to create three-dimensional compact liposome networks, adhered to topographic substrates fabricated in the epoxy polymer SU-8 was described. The polymeric photoresist SU-8 is a highly suitable material for soybean lipid vesicle immobilization displaying sufficient contact potential for secure anchoring of liposomes and minimal lipid spreading. The material allows fluid-state lipid membrane structures to retain their structural integrity for long time periods. The use of the construction techniques increases the compactness of lipid nanotube networks as the tube density from a single vesicle is increased when access to the off-equatorial area is provided.