Carbon-carbon and carbon-heteroatom bond formation on solid phase using cationic iron carbonyl complexes
Artikel i vetenskaplig tidskrift, 2005

Iron-mediated methodology for the formation of carbon-carbon and carbon-heteroatom sp(3) bonds on solid phase has been developed. Treatment of a polymer-bound cationic iron cyclohexadienyl complex with carbon, oxygen, nitrogen, and phosphorus nucleophiles, followed by cleavage with amines and subsequent decomplexation, yielded 18 different cyclohexadienoic acid amides of high purity.

solid phase organic synthesis

organometallic

dienyl complex

iron carbonyl

iron

Författare

Henrik Gradén

Chalmers, Kemi- och bioteknik, Organisk och analytisk kemi

T. Olsson

AstraZeneca Sweden

Nina Kann

Chalmers, Kemi- och bioteknik, Organisk och analytisk kemi

Organic Letters

1523-7060 (ISSN) 1523-7052 (eISSN)

Vol. 7 3565-3567

Ämneskategorier

Organisk kemi

DOI

10.1021/ol051353b