Conversion of dehydroascorbic acid to a branched hexaric acid in neutral and alkaline aqueous solution
Artikel i vetenskaplig tidskrift, 1976

Dehydroascorbic acid is shown to be converted to 2-(threo-1,2,3-trihydroxypropyl)tartronic acid in aqueous alkaline solutions. The structure of the acid was determined by mass spectrometry of its acyclic Me3Si derivative. Mass spectrometric and chromatographic data are compared with those of related compounds. The acid is formed by a benzilic acid rearrangement of the intermediate 2,3-hexodiulosonic acid. The rate of formation at 38°C was studied quantitatively by glc. It increases at increased alkalinity but is significant even at physiological pH. The presence of oxygen does not substantially influence the reaction.

Författare

Göran Petersson

Institutionen för teknisk kemi

Analytical Biochemistry

Vol. 72 623-628

Ämneskategorier

Analytisk kemi

Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci)

DOI

10.1016/0003-2697(76)90575-3