Carbohydrate - related hydroxy carboxylic and dicarboxylic acids as trimethylsilyl derivatives

Artikel i vetenskaplig tidskrift, 1977

Retention index and relative retention were determined for trimethylsilyl esters/ethers of approximately 170 acids and lactones. The structural categories studied were aldonic (hydroxy monocarboxylic) acids, aldaric (hydroxy dicarboxylic) acids, non - carbohydrate (mainly dicarboxylic) acids, and lactones of aldonic acids. Data are given for the silicone stationary phases OV-1 (methyl), OV-17 (50% phenyl) and QF-1 (50% trifluoropropyl). Diagrams of the retention index on the non-polar phase versus the increase in the retention index on either of the other phases are useful for qualitative analysis. The dependence of retention on structure is interpreted in terms of non-polar and polar interactions between solute and stationary phase. Structural units of the solutes are attributed retention index increments which permit predictions of retention from structure or structure from retention. The reference retention index data can be used in temperature - programmed analalysis if retentions are measured as methylene unit (MU) values. Differences between the retention index and MU concepts are discussed.