Exact equilibrium state solution of an intracellular complex formation model: kA↔P reaction in a small volume

Artikel i vetenskaplig tidskrift, 2010

A generic model of complex formation in small volumes was studied under the assumption of perfect mixing. Particles A react in clusters, and each reaction converts k A particles into a P particle. The back reaction is also allowed. The equilibrium state of the model is solved exactly. Fluctuations in product particle number are reduced by increasing the degree of cooperativity k. Three qualitatively distinct reactant fluctuation characteristics emerge.