Surface adsorption of fibronectin-derived peptide fragments: the influence of electrostatics and hydrophobicity for endothelial cells adhesion
Artikel i vetenskaplig tidskrift, 2012

The adsorption on hydrophobic and hydrophilic silica-based surfaces of the integrin-binding PHSRN peptide and the single-residual-mutated analogues, PHSEN and PHSFN, is investigated by comparative QCM-D, XPS, SFG measurements and molecular dynamics calculations. Endothelial cell cultures on the peptide-functionalized materials highlight their tunable pro- or anti-angiogenic potential.

interfaces

molecules

monolayers

sum-frequency generation

Författare

C. Satriano

Universita degli Studi di Catania

M. E. Fragala

Universita degli Studi di Catania

G. Forte

Universita degli Studi di Catania

A. M. Santoro

Consiglio Nazionale delle Ricerche

D. La Mendola

Consiglio Nazionale delle Ricerche

Bengt Herbert Kasemo

Chalmers, Teknisk fysik, Kemisk fysik

Soft Matter

1744-683X (ISSN) 1744-6848 (eISSN)

Vol. 8 53-56

Ämneskategorier

Kemi

DOI

10.1039/c1sm06655b