Sequence-Specific Crosslinking of Electrospun, Elastin-Like Protein Preserves Bioactivity and Native-Like Mechanics.
Artikel i vetenskaplig tidskrift, 2013

A nanoscale mimic of the extracellular matrix is electrospun from a highly tunable family of elastin-like proteins. A sequence-specific, two-step crosslinking procedure is developed to preserve the nanofiber morphology, elastin-like mechanics, and specific bioactivity. Rodent marrow stromal cells show sequence-specific adhesion on the matrices, which are imaged using label-free coherent anti-Stokes Raman scattering (CARS) microscopy.

Författare

Patrick L Benitez

Stanford University

Jeffrey A Sweet

Stanford University

Helen Fink

Chalmers, Kemi- och bioteknik, Molekylär mikroskopi

Krishna P Chennazhi

Amrita Vishwa Vidyapeetham University, Kochi

Shantikumar V Nair

Amrita Vishwa Vidyapeetham University, Kochi

Annika Enejder

Chalmers, Kemi- och bioteknik, Molekylär mikroskopi

S. C. Heilshorn

Stanford University

Advanced healthcare materials

2192-2640 (ISSN) 2192-2659 (eISSN)

Vol. 2 114-118

Ämneskategorier

Annan medicin och hälsovetenskap

DOI

10.1002/adhm.201200115

PubMed

23184558