The impact of temperature on the metabolome and endocrine metabolic signals in Atlantic salmon (Salmo salar)
Artikel i vetenskaplig tidskrift, 2013

The aim was to elucidate the effects of elevated temperature on growth performance, growth- and appetite-regulating hormones and metabolism in Atlantic salmon, Salmo salar. Post-smolts in seawater (average mass 175 g) that had been reared at 12 °C were kept at three temperatures (8, 12 and 18 °C) and sampled after one and three months. After three months, the fish kept in 18 °C had decreased growth rate and condition factor, and elevated plasma levels of growth hormone (GH) and leptin, compared with fish kept at the lower temperatures. Food conversion efficiency was also decreased at 18 °C, while at the same time protein uptake was improved and thus was not a limiting mechanism for growth. Redistribution of energy stores in fish at the highest temperature is evident as a preference of maintaining length growth during times of limited energy availability. NMR-based metabolomics analyses of plasma revealed that several metabolites involved in energy metabolism were negatively affected by temperature in the upper temperature range of Atlantic salmon. Specifically, the high temperature induced a decline of several amino acids (glutamine, tyrosine and phenylalanine) and a shift in lipid metabolism. It appears likely that the decreased food intake at the highest temperature is linked to an anorexigenic function of leptin, but also that the decreased food intake, feed conversion efficiency and condition factor can be linked to changes in GH endocrinology.

Fish condition factor endocrinology growth NMR metabolomics metabolism temperature

Författare

Andreas Kullgren

Göteborgs universitet

Fredrik Jutfelt

Göteborgs universitet

Ramon Fontanillas

Nutreco Aquaculture Research Centre

Kristina Sundell

Göteborgs universitet

Linda Samuelsson

Göteborgs universitet

Kerstin Wiklander

Göteborgs universitet

Chalmers, Matematiska vetenskaper, matematisk statistik

Peter Kling

Göteborgs universitet

Wolfgang Koppe

Nutreco Aquaculture Research Centre

D. G. Joakim Larsson

Göteborgs universitet

Björn Thrandur Björnsson

Göteborgs universitet

Elisabeth Jönsson

Göteborgs universitet

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology

1095-6433 (ISSN) 1531-4332 (eISSN)

Vol. 164 1 44-53

Ämneskategorier

Biologiska vetenskaper

Zoologi

DOI

10.1016/j.cbpa.2012.10.005