Acoustic monitoring of changes in well-defined hyaluronan layers exposed to chondrocytes
Artikel i vetenskaplig tidskrift, 2014

The interaction of human-derived chondrocytes and thin hyaluronan layers was studied using the quartz crystal microbalance with dissipation (QCM-D) technique combined with light microscopy. This approach allowed unique real-time monitoring of the interface between the cells and the sensor surface. Our results suggest that the hyaluronan layer is rapidly degraded by chondrocytes.

Chemistry

DEGRADATION

QCM-D

Analytical

CELL

Författare

Erik Nilebäck

Chalmers, Teknisk fysik, Biologisk fysik

Lars Enochson

Göteborgs universitet

Noomi Altgärde

Chalmers, Teknisk fysik, Biologisk fysik

Matthias Schnabelrauch

Biomaterials Department

Anders Lindahl

Göteborgs universitet

Sofia Svedhem

Chalmers, Teknisk fysik, Biologisk fysik

Angelika Kunze

Chalmers, Teknisk fysik, Biologisk fysik

The Analyst

0003-2654 (ISSN) 1364-5528 (eISSN)

Vol. 139 5350-5353

Ämneskategorier

Analytisk kemi

DOI

10.1039/c4an01393j