Human Milk: Its Components and Their Immunobiologic Functions
Kapitel i bok, 2015

Whereas a neonate is born is sterile, immediate exposure to its mother's mucosal surfaces allows it to acquire microflora, which plays an important role in defense against potential pathogens. This initial stimulus helps the immature immune system of the newborn to develop the capacity to respond with specific immunologic tolerance while avoiding the development of allergic and autoimmune disease. Breast-feeding provides nutritional and developmental, along with anti-infectious, advantages to the infant. The significant protection conferred by breast-feeding against varied infections such as acute and prolonged diarrhea, neonatal septicemia, respiratory tract infections, acute and recurrent otitis media, and urinary tract infections is observed worldwide. Human breast milk contains numerous components, including antibodies, cytokines, hormones, enzymes, and major proteins with multiple activities (microbicidal, tumoricidal, anti-inflammatory, autoimmune, etc.). Breast-feeding can strikingly reduce infant mortality, as well as the fertility of the breast-feeding mother. In this manner, breast-feeding provides significant benefits for lactating mothers and their offspring, in addition to society as a whole. © 2015 Elsevier Inc. All rights reserved.

Atopy

Neonate

Infant mortality

Tumoricidal

Human milk

Microbicidal

Anti-inflammatory

Obesity

Författare

Dulal Ravi Sharma

Chalmers, Mikroteknologi och nanovetenskap (MC2), Kvantkomponentfysik

Lars Åke Hanson

Göteborgs universitet

Marina Korotkova

Göteborgs universitet

Esbjörn Telemo

Göteborgs universitet

P. Ogra

Mucosal Immunology: Fourth Edition. Volume 2

Vol. 2-2 2307-2341

Ämneskategorier

Immunologi inom det medicinska området

DOI

10.1016/B978-0-12-415847-4.00117-8

ISBN

978-0-12-415847-4

Mer information

Skapat

2017-10-08