Attractive aerobic access to the α,β-unsaturated acyl azolium intermediate: oxidative NHC catalysis via multistep electron transfer
Artikel i vetenskaplig tidskrift, 2016
To replace high molecular weight oxidants with air (O2) we introduce multistep electron transfer NHC catalysis. The method provides a general and selective oxidation of the α,β-unsaturated aldehyde derived homoenolate to the synthetically useful α,β-unsaturated acyl azolium intermediate. Several independent oxidative NHC-catalyzed reactions are viable with this strategy and the products can be isolated in high to excellent yields.
N-heterocyclic carbene
NHC
oxidation
Green Chemistry
organocatalysis
Electron transfer mediators
Aerobic
Författare
Linda Ta
Chalmers, Kemi och kemiteknik, Kemi och biokemi
Anton Axelsson
Chalmers, Kemi och kemiteknik, Kemi och biokemi
Henrik Sundén
Chalmers, Kemi och kemiteknik, Kemi och biokemi
Green Chemistry
1463-9262 (ISSN) 1463-9270 (eISSN)
Vol. 18 3 686-690Drivkrafter
Hållbar utveckling
Ämneskategorier
Kemi
Organisk kemi
DOI
10.1039/C5GC01965F