Attractive aerobic access to the α,β-unsaturated acyl azolium intermediate: oxidative NHC catalysis via multistep electron transfer
Artikel i vetenskaplig tidskrift, 2016

To replace high molecular weight oxidants with air (O2) we introduce multistep electron transfer NHC catalysis. The method provides a general and selective oxidation of the α,β-unsaturated aldehyde derived homoenolate to the synthetically useful α,β-unsaturated acyl azolium intermediate. Several independent oxidative NHC-catalyzed reactions are viable with this strategy and the products can be isolated in high to excellent yields.

N-heterocyclic carbene

NHC

oxidation

Green Chemistry

organocatalysis

Electron transfer mediators

Aerobic

Författare

Linda Ta

Kemi och kemiteknik, Kemi och biokemi, Organisk kemi

Anton Axelsson

Kemi och kemiteknik, Kemi och biokemi, Organisk kemi

Henrik Sundén

Kemi och kemiteknik, Kemi och biokemi, Organisk kemi

Green Chemistry

1463-9262 (ISSN) 1463-9270 (eISSN)

Vol. 18 686-690

Drivkrafter

Hållbar utveckling

Ämneskategorier

Kemi

Organisk kemi

DOI

10.1039/C5GC01965F