Quality assurance guidelines for superficial hyperthermia clinical trials
Artikel i vetenskaplig tidskrift, 2017

Quality assurance (QA) guidelines are essential to provide uniform execution of clinical trials with uniform quality hyperthermia treatments. This document outlines the requirements for appropriate QA of all current superficial heating equipment including electromagnetic (radiative and capacitive), ultrasound, and infrared heating techniques. Detailed instructions are provided how to characterize and document the performance of these hyperthermia applicators in order to apply reproducible hyperthermia treatments of uniform high quality. Earlier documents used specific absorption rate (SAR) to define and characterize applicator performance. In these QA guidelines, temperature rise is the leading parameter for characterization of applicator performance. The intention of this approach is that characterization can be achieved with affordable equipment and easy-to-implement procedures. These characteristics are essential to establish for each individual applicator the specific maximum size and depth of tumors that can be heated adequately. The guidelines in this document are supplemented with a second set of guidelines focusing on the clinical application. Both sets of guidelines were developed by the European Society for Hyperthermic Oncology (ESHO) Technical Committee with participation of senior Society of Thermal Medicine (STM) members and members of the Atzelsberg Circle.

Heating criteria

superficial

Applicator

Quality assurance

Phantoms

Water bolus

Hyperthermia

Författare

Hana Dobsicek Trefna

Chalmers, Signaler och system, Signalbehandling och medicinsk teknik, Biomedicinsk elektromagnetik

J. Crezee

Universiteit Van Amsterdam

M. Schmidt

Universitatsklinik Erlangen und Medizinische Fakultat

D. Marder

Kantonsspital Aarau

U. Lamprecht

Universitatsklinikum Tubingen Medizinische Fakultat

M. Ehmann

Universitatsklinikum Mannheim

J. Nadobny

Charité Universitätsmedizin Berlin

J. Hartmann

Universitatsklinik Erlangen und Medizinische Fakultat

N. Lomax

Kantonsspital Aarau

S. Abdel-Rahman

Ludwig-Maximilians-Universität München

S. Curto

Erasmus University Medical Center

A. Bakker

Universiteit Van Amsterdam

M. D. Hurwitz

Thomas Jefferson University

C. J. Diederich

University of California

P. R. Stauffer

Thomas Jefferson University

G. C. Van Rhoon

Erasmus University Medical Center

Strahlentherapie und Onkologie

0179-7158 (ISSN) 1439-099X (eISSN)

Vol. 193 5 351-366

Ämneskategorier

Klinisk medicin

Medicinteknik

DOI

10.1007/s00066-017-1106-0