Selective Iron-Mediated C- and O-Addition of Phenolic Nucleophiles to a Cyclohexadiene Scaffold Using Renewable Precursors
Artikel i vetenskaplig tidskrift, 2019

Renewable phenols have been investigated as nucleophiles for the addition to a cationic cyclohexadienyl iron carbonyl scaffold. Benign conditions compatible with solvents such as ethanol and water were developed, and for the first time, selective C- or O-addition could be achieved. In addition, a novel atom-economic approach to forming the C-addition products directly from the neutral precursor complex in a single step using a catalytic acid is described. The formed C-addition product could then be selectively demetalated to form one of two different product classes, a functionalized arene or a cyclohexadiene.



Renewable resources


Metal carbonyl

Green chemistry



Petter Dunås

Chalmers, Kemi och kemiteknik, Kemi och biokemi

Andrew Paterson

Chalmers, Kemi och kemiteknik, Kemi och biokemi

G. Kociok-Köhn

University of Bath

Simon E. Lewis

University of Bath

Nina Kann

Chalmers, Kemi och kemiteknik, Kemi och biokemi

ACS Sustainable Chemistry & Engineering

2168-0485 (eISSN)

Vol. 7 7 7155-7162


Kemiska processer

Biokatalys och enzymteknik

Organisk kemi



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