Characterization and modeling of acousto-optic signal strengths in highly scattering media
Artikel i vetenskaplig tidskrift, 2019

Ultrasound optical tomography (UOT) is an imaging technique based on the acousto-optic effect that can perform optical imaging with ultrasound resolution inside turbid media, and is thus interesting for biomedical applications, e.g. for assessing tissue blood oxygenation. In this paper, we present near background free measurements of UOT signal strengths using slow light filter signal detection. We carefully analyze each part of our experimental setup and match measured signal strengths with calculations based on diffusion theory. This agreement between experiment and theory allows us to assert the deep tissue imaging potential of similar to 5 cm for UOT of real human tissues predicted by previous theoretical studies [Biomed. Opt. Express 8, 4523 (2017)] with greater confidence, and indicate that future theoretical analysis of optimized UOT systems can be expected to be reliable. (C) 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreement

Författare

Alexander Bengtsson

Lunds universitet

David Hill

Lunds universitet

SpectraCure AB

Meng Li

Lunds universitet

Mengqiao Di

Lunds universitet

Chalmers, Kemi och kemiteknik, Tillämpad kemi, Per-Anders Carlsson Group

Magnus Cinthio

Lunds universitet

Tobias Erlov

Lunds universitet

Stefan Andersson-Engels

Tyndall Natl Inst

University College Cork

Nina Reistad

Lunds universitet

Andreas Walther

Lunds universitet

Lars Rippe

Lunds universitet

Stefan Kroll

Lunds universitet

Biomedical Optics Express

2156-7085 (ISSN)

Vol. 10 11 5565-5584

Ämneskategorier

Medicinsk laboratorie- och mätteknik

Atom- och molekylfysik och optik

DOI

10.1364/BOE.10.005565

Mer information

Senast uppdaterat

2019-12-06