Diet with greater inflammatory potential is associated with higher prevalence of fatty liver among US adults
Artikel i vetenskaplig tidskrift, 2019

The prevalence of non-alcoholic fatty liver disease (NAFLD) is rising—caused, at least in part, by unhealthy lifestyles including poor dietary choices. We examined the link between the inflammatory potential of diet as measured by the Dietary Inflammatory Index (DII®) and liver function tests [summarised by the fatty liver index (FLI)]. Of 20,643 US NHANES participants, 48.7% were men and the mean age was 47.3 years. Significant associations were apparent between increasing DII score and prevalent fatty liver. Individuals in the fourth DII quartile had nearly a six-fold higher likelihood of fatty liver [odds ratio (OR) = 5.97, 95% confidence interval: 4.44–8.02] compared with those in the first quartile. Moderation analysis indicated a significant impact of adiposity on the link between FLI and DII score (p < 0.001). This study provides further evidence of an association between the inflammatory potential of diet and fatty liver.© 2018, Springer Nature Limited.


Mohsen Mazidi

Chalmers, Biologi och bioteknik, Livsmedelsvetenskap

Nitin Shivappa

Connecting Health Innovations

University of South Carolina

Connecting Health Innovations LLC

Michael D. Wirth

Connecting Health Innovations LLC

University of South Carolina

James R. Hebert

Connecting Health Innovations LLC

University of South Carolina

Andre Pascal Kengne

South African Medical Research Council

European Journal of Clinical Nutrition

0954-3007 (ISSN) 14765640 (eISSN)

Vol. 73 12 1653-1656









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