A Four Parameter Microfluidic Tandem SAW-IS Bio-Sensor
Paper i proceeding, 2019

Surface Acoustic Resonance (SAR) biosensing has recently been proposed as a highly compact and robust alternative to the conventional SAW delay-line based biosensing. The device can also be presented as a one-port high frequency alternative to the QCM, employing SAW resonance. It enables simple one-port measurements at low powers, while offering robust integration with microfluidics and implementation in integrated sensor arrays. Here we discuss the SAR approach as a key enabling and demonstrate its integration with the impedance spectroscopy (IS) concept in a single microfluidic device. The IS is integrated within a SAW reflector formed as interdigitated electrode (IDE) capacitor. A test fixture with SAW and IS ports is designed and fabricated. Four sensitive parameters are deduced from the tandem sensor readout and employed in a proof of principle study of liposome layers and their interaction with Ca2+ ions.

high sensitivity

low power

SAW

impedance spectroscopy

biosensing

Författare

Ventsislav Yantchev

Q-Arts Consulting EOOD

Kiryl Kustanovich

Chalmers, Kemi och kemiteknik, Kemi och biokemi, Fysikalisk kemi

A. Jesorka

Q-Arts Consulting EOOD

IEEE International Ultrasonics Symposium, IUS

19485719 (ISSN) 19485727 (eISSN)

Vol. 2019-October 193-196 8926159

2019 IEEE International Ultrasonics Symposium, IUS 2019
Glasgow, United Kingdom,

Ämneskategorier

Medicinsk laboratorie- och mätteknik

Medicinsk apparatteknik

Annan elektroteknik och elektronik

DOI

10.1109/ULTSYM.2019.8926159

Mer information

Senast uppdaterat

2020-04-16