Subcompartmentalization and Pseudo-Division of Model Protocells
Artikel i vetenskaplig tidskrift, 2020

Membrane enclosed intracellular compartments have been exclusively associated with the eukaryotes, represented by the highly compartmentalized last eukaryotic common ancestor. Recent evidence showing the presence of membranous compartments with specific functions in archaea and bacteria makes it conceivable that the last universal common ancestor and its hypothetical precursor, the protocell, may have exhibited compartmentalization. To the authors' knowledge, there are no experimental studies yet that have tested this hypothesis. They report on an autonomous subcompartmentalization mechanism for protocells which results in the transformation of initial subcompartments to daughter protocells. The process is solely determined by the fundamental materials properties and interfacial events, and does not require biological machinery or chemical energy supply. In the light of the authors' findings, it is proposed that similar events may have taken place under early Earth conditions, leading to the development of compartmentalized cells and potentially, primitive division.

solid surfaces

wetting

origin of life

protocells

compartments

Författare

Karolina Spustova

Universitetet i Oslo

Elif Senem Koksal

Universitetet i Oslo

Alar Ainla

Chalmers, Kemi och kemiteknik, Kemi och biokemi, Fysikalisk kemi

Irep Gözen

Chalmers, Kemi och kemiteknik, Kemi och biokemi

Small

1613-6810 (ISSN) 1613-6829 (eISSN)

Vol. in press 2005320

Ämneskategorier

Biokemi och molekylärbiologi

Annan kemiteknik

Biofysik

DOI

10.1002/smll.202005320

PubMed

33230918

Mer information

Senast uppdaterat

2020-12-14