Novel strains with superior degrading efficiency for lincomycin manufacturing biowaste
Artikel i vetenskaplig tidskrift, 2021

As the antibiotic pollution source in the environment, a large amount of biowastes generated from antibiotic fermentation manufacture needs proper disposal. Recycling the biowaste as resources and nutrients is of great interest. Besides, degradation or removal of antibiotics is indispensable for the reclamation of antibiotic manufacturing biowaste. To establish environmentally friendly disposal strategies for lincomycin manufacturing biowaste (LMB), we screened the microbial strains that could efficiently degrade lincomycin from the antibiotic wastewater treatment plant. Among them, three novel strains were identified as Bacillus subtilis (strain LMB-A), Rhodotorula mucilaginosa (strain LMB-D) and Penicillium oxalicum (strain LMB-E), respectively. LMB-A and LMB-D could degrade 92.69% and 74.05% of lincomycin with an initial concentration of 1117.55 mg/L in 144 h, respectively. The lincomycin degradation products were formed by the breakage of amide bond or losing N-demethyl/thiomethyl group from the pyrrolidine/pyranose ringcata cata catalyzed by the strains. Moreover, LMB-A could decontaminate LMB, and the decontaminated LMB could be used as a nitrogen source to culture salt-resistant bacteria and other useful microorganisms. LMB-A and LMB-D have the potential to be used for the bioremediation of water and soil polluted by lincomycin and its analogs. LMB-E could degrade 88.20% LMB after 144-h cultivation. In summary, this study gives an insight into the green disposal of LMB, and the established strategy has potential application for biotreatment of other antibiotic fermentation manufacturing biowastes.

Lincomycin manufacturing biowaste

Bioremediation

Lincomycin biodegradation

Biotreatment

Författare

Yonghong Li

Zhengzhou University

Luping Fu

Zhengzhou University

Xuan Li

Zhengzhou University

Yun Wang

Zhengzhou University

Yongjun Wei

Zhengzhou University

Jinfeng Tang

Guangzhou University

Chalmers, Kemi och kemiteknik, Energi och material, Kärnkemi

Hongmin Liu

Zhengzhou University

Ecotoxicology and Environmental Safety

0147-6513 (ISSN) 1090-2414 (eISSN)

Vol. 209 111802

Ämneskategorier

Annan naturresursteknik

Mikrobiologi

Vattenbehandling

DOI

10.1016/j.ecoenv.2020.111802

PubMed

33360784

Mer information

Senast uppdaterat

2021-02-24