Upper Respiratory Tract Levels of Severe Acute Respiratory Syndrome Coronavirus 2 RNA and Duration of Viral RNA Shedding Do Not Differ Between Patients With Mild and Severe/Critical Coronavirus Disease 2019
Artikel i vetenskaplig tidskrift, 2021
This study reports longitudinal viral RNA loads from the nasopharynx/throat in patients with mild and severe/critical coronavirus disease 2019 (COVID-19). We also investigated whether the duration of symptoms correlated with the duration of viral RNA shedding. A total of 56 patients were included. The highest viral loads occurred early after onset of symptoms. Neither the viral RNA loads in the upper respiratory tract nor the time to viral RNA clearance differed between patients with mild or severe/critical disease. There was a moderate correlation between number of days with symptoms and number of days with viral RNA shedding in patients with mild COVID-19.
SARS-CoV-2
nasopharynx
viral shedding
COVID-19
Författare
Aylin Yilmaz
Sahlgrenska universitetssjukhuset
Göteborgs universitet
Emelie Marklund
Göteborgs universitet
Sahlgrenska universitetssjukhuset
Maria Andersson
Göteborgs universitet
Staffan Nilsson
Chalmers, Matematiska vetenskaper, Tillämpad matematik och statistik
Lars-Magnus Andersson
Göteborgs universitet
Sahlgrenska universitetssjukhuset
Magnus Lindh
Göteborgs universitet
Magnus Gisslen
Göteborgs universitet
Sahlgrenska universitetssjukhuset
Journal of Infectious Diseases
0022-1899 (ISSN) 1537-6613 (eISSN)
Vol. 223 1 15-18Ämneskategorier
Kirurgi
Gastroenterologi
Lungmedicin och allergi
Reumatologi och inflammation
DOI
10.1093/infdis/jiaa632
PubMed
33020822