A selected review of recent advances in the study of neuronal circuits using fiber photometry
Reviewartikel, 2021

To understand the correlation between animal behaviors and the underlying neuronal circuits, it is important to monitor and record neurotransmission in the brain of freely moving animals. With the development of fiber photometry, based on genetically encoded biosensors, and novel electrochemical biosensors, it is possible to measure some key neuronal transmission events specific to cell types or neurotransmitters of interest with high temporospatial resolution. This review discusses the recent advances and achievements of these two techniques in the study of neurotransmission in animal models and how they can be used to complement other techniques in the neuroscientist's toolbox.

Electrochemical biosensor

Genetically-encoded biosensor

Fiber photometry

Neuronal circuits

Brain mapping

Neurotransmission

Författare

Yuanmo Wang

Chalmers, Kemi och kemiteknik, Kemi och biokemi

Emily M. DeMarco

University of Maryland, Baltimore

Lisa Sophia Witzel

New York Institute of Technology

Jacqueline D. Keighron

New York Institute of Technology

Pharmacology Biochemistry and Behavior

0091-3057 (ISSN)

Vol. 201 173113

Ämneskategorier

Neurovetenskaper

Farmakologi och toxikologi

DOI

10.1016/j.pbb.2021.173113

PubMed

33444597

Mer information

Senast uppdaterat

2021-03-17