Severe COVID-19 in people 55 and older during the first year of the pandemic in Sweden
Artikel i vetenskaplig tidskrift, 2022

Background
Exposure to many contacts is the main risk factor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, while risk of serious disease and death is chiefly determined by old age and comorbidities. Relative and population-attributable fractions (PAFs) of multiple medical and social exposures for COVID-19 outcomes have not been evaluated among older adults.
Objectives
We describe the effect of multiple exposures on the odds of testing positive for the virus and of severe disease (hospital care or death) and PAFs in Swedish citizens aged 55 years and above.
Methods
We used national registers to follow all citizens aged 55 years and above with respect to (1) testing positive, (2) hospitalization, and (3) death between 31 January 2020 and 1 February 2021.
Results
Of 3,410,241 persons, 156,017 (4.6%, mean age 68.3 years) tested positive for SARS-CoV-2, while 35,999 (1.1%, mean age 76.7 years) were hospitalized or died (12,384 deaths, 0.4%, mean age 84.0 years). Among the total cohort, the proportion living without home care or long-term care was 98.8% among persons aged 55–64 and 22.1% of those aged 95 and above. After multiple adjustment, home care and long-term care were associated with odds ratios of 7.9 (95% confidence interval [CI] 6.8–9.1) and 22.5 (95% CI 19.6–25.7) for mortality, with PAFs of 21.9% (95% CI 20.9–22.9) and 33.3% (95% CI 32.4–34.3), respectively.
Conclusion
Among Swedish residents aged 55 years and above, those with home care or long-term care had markedly increased risk for COVID-19 death during the first year of the pandemic, with over 50% of deaths attributable to these factors.

Författare

Annika Rosengren

Göteborgs universitet

Christina E. Lundberg

Göteborgs universitet

Mia Söderberg

Göteborgs universitet

Ailiana Santosa

Göteborgs universitet

Jon Edqvist

Göteborgs universitet

Martin Lindgren

Göteborgs universitet

Maria Åberg

Västra Götalandsregionen

Göteborgs universitet

Magnus Gisslen

Sahlgrenska universitetssjukhuset

Göteborgs universitet

Josefina Robertson

Göteborgs universitet

Sahlgrenska universitetssjukhuset

Ottmar Cronie

Chalmers, Matematiska vetenskaper, Tillämpad matematik och statistik

Göteborgs universitet

Naveed Sattar

Göteborgs universitet

University of Glasgow

Jesper Lagergren

King's College London

Karolinska universitetssjukhuset

Maria Brandén

Linköpings universitet

Stockholms universitet

Jonas Björk

Lunds universitet

Skånes universitetssjukhus (SUS)

Martin Adiels

Göteborgs universitet

Journal of Internal Medicine, Supplement

0955-7873 (ISSN)

Vol. 292 4 641-653

Ämneskategorier

Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi

DOI

10.1111/joim.13522

Mer information

Senast uppdaterat

2023-10-26